CHEM 475 Fall 2005 Laboratory Exercises

Last Update: August 23, 2006

 

By the end of the semester you are required to complete seven exercises from the following groups. All experiments are subject to reagent availability, the demands of scheduling and the instructor’s whim.

 

In all exercises the minimum characterization that is required includes: the IR spectrum, the UV-Vis spectrum with molar absorptivities (if colored and soluble), and either the 1H and 13C NMR spectra (if diamagnetic) or magnetic moment (if paramagnetic). Melting points should be determined only for compounds whose melting points are reported to be less than 200 °C.

 

Characterization beyond the minimum required (e. g., X-ray structure determination, cyclic voltammetry, etc.) will be rewarded. You must clear any additional work with your instructor before attempting any work of this sort!

 

In some of the exercises the identity of the product is not given. You will need to identify the product (or products) using standard methods and the additional information that you will be provided. In these cases you are also free to use any other method of analysis that we have at Truman, but you must clear it with your instructor first.

 

IMPORTANT! Some of these experiments are more challenging than others! You will be rewarded for attempting them, even if you do not get a “final” result.

 

Macrocyles (choose 2)

In these exercises you will first prepare the ligand and once the ligand has been synthesized you may choose which metal complex to synthesize. For the two template syntheses you will need to remove the metal template, and put a different metal in.

Synthesis of a Porphyrin and its Metal Complex
Template Synthesis of a Macrocyclic Ligand
Template Synthesis of a Schiff-Base Macrocycle
Non-Template Macrocyclic Ligand Synthesis

 

Organometallics (choose 2)

You may choose one, but not both, of the exercises involving the Mo-Mo quadruple bond.

Synthesis of a Tin Organometallic
Synthesis of (η6-1, 3, 5-Methylbenzene)tricarbonylmolybdenum(0)
A Cobalt-Dimethylglyoxime Complex as a Model for Cobalamin
Preparation of a Molybdenum-Phosphine Complex Containing a Mo-Mo Quadruple Bond
Preparation of an Anisylformamidinate Complex Containing a Mo-Mo Quadruple Bond

 

Miscellaneous Exercises (choose 2)

You can choose one, but not two, of the exercises involving acetylacetonate.

Synthesis and Characterization of a Cobalt-SALEN Oxygen Carrier
Synthesis of an Epoxidation Catalyst
Preparation of O2x- Bridged Cobalt Compounds
Dithiolene Complexes
Synthesis of the Aluminum Complex of Acetylacetonate
Synthesis of Dipyridineiodine(I) Nitrate
Resolution of [Co(en)3]3+

 

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